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The inability of affected cell to clear nonfunctionally associated PD-specific Syn variants with endogenous proteins has a detrimental effect on postmitotic neurons, a phenomenon previously reported in prion-infected cells 82

J Psychiatr Res 75:7581

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For instance, certain polyphenols have been used to treat tumors, such as in one study where the treatment of breast cancer cells with resveratrol resulted in differential expression of several genes related to the cell cycle and induced S-phase arrest (71)