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However, the chronic inflammatory state that arises in diabetes leads to continuous ROS production, resulting in cellular damage and the depletion of antioxidant systems [9]

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Similar content being viewed by others Background Neurofibromatosis type 1 (NF1), first characterised in detail by the German pathologist Friedrich von Recklinghausen in 1882, is an autosomal-dominant genetic disorder that results from biallelic inactivation of the tumour-suppressor gene NF1