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In the PI3K-Akt signalling pathway, the expression levels of the critical regulatory factor CXCL9 (42) were significantly lower in the IAP + LPS group than in the LPS group

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As you can see from the diagram, the bioactive folate donates a methyl group to the amino acid homocysteine, which is then able to convert into methionine, which further goes on to form SAMe

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