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(1996) Gastric antioxidants, nitrites, and mucosal lipoperoxidation in chronic gastritis and Helicobacter pylori infection

An imbalance in ROS-induced ROS release may trigger various cellular signaling pathways with the consequent onset of numerous pathologies, including cell death [6]

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To cite an example, superoxide dismutase (SOD), especially Mn-SOD, a representative of protective enzymes that neutralized reactive oxygen species (ROS), which were inducers of inflammation in various diseases, was measured reduced in inflamed tissue from IBD patients [35]