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Cubero F, Singh A, Borkham-Kamphorst E, Nevzorova Y, Al Masaoudi M, Haas U, Boekschoten M, Gassler N, Weiskirchen R, Muller M (2013) TNFR1 determines progression of chronic liver injury in the IKK/Nemo genetic model

A coffee enema rather than an oral dose was utilized in this study because 1 L of coffee extract is difficult to ingest in addition to the customary 2 L of PEG, and the coffee solution itself could impede VCE

This adaptation presents a targetable vulnerability whereby the functional inhibition of this adaptive response greatly increased the effectiveness of 5FU across CRC models in vitro and in vivo

Th1 cells are primary secretors of interferon (IFN-), a type II interferon able to incite pSS formation [9]