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The SASP is regulated by complex signaling networks, often involving transcription factors like NF-B and C/EBP, and can be reinforced by autocrine feedback loops involving factors like IL-1 [20]

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Control of cell death by transcriptional regulation of the apoptotic machinery

Schwender K, Holtktter H, Johann KS, Glaub A, Schrenkamp M, Sibbing U, Banken S, Vennemann M, Pfeiffer H, Vennemann M, GeSID Study Group (2016) Sudden infant death syndrome: exposure to cigarette smoke leads to hypomethylation upstream of the growth factor independent 1 (GFI1) gene promoter