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PGC-1 upregulation induces NRF1/2 and TFAM expression, supporting mtDNA replication and respiratory chain activity

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Aging is fundamentally a progressive decline in organ function and accumulation of pathological damage across multiple systems, necessitating long-term, multidimensional interventions for effective mitigation (46)

Thanks to its sticky sulfur component, glutathione plays a key role in the removal of several toxins, by acting as a conjugate that attaches to those small molecules and enables their excretion through bile