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In the nucleus, receptor dimers bind to androgen response elements (AREs) in the promoter regions of target genes, such as prostate-specific antigen (PSA) and transmembrane protease serine 2 (TMPRSS2), etc , to which they recruit various coregulatory proteins to facilitate transcription, leading to responses such as growth and survival 7,8,9,10,11,12

It is always wise to speak to a doctor when changing your diet, particularly if you have a health condition or any other restrictions on your diet

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The DSM-5, ICSD-3, and ICD-11 recognise this by allowing co-morbidity outright