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The results have been striking: GHK-Cu has been shown to modulate the expression of more than 4,000 human genes, with the net effect being a return toward expression patterns associated with younger, healthier tissue.6 The pathways most consistently affected include antioxidant defense (upregulation of catalase, superoxide dismutase, and glutathione synthesis), DNA damage repair, extracellular matrix remodeling, and anti-inflammatory signaling

The theory is that microneedling creates controlled micro-injuries that trigger the wound healing cascade, while GHK-Cu supercharges the collagen production response during that healing window

This finding has significant implications for anyone who has received steroid injections for hip problems and may be experiencing delayed recovery as a result

Steven Ganzel for fluoroscopy-guided epidural injections