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It helps regulate actin, a key protein in cell structure and movement, which is fundamental to the healing process

The exchange of glutamate, GABA, and glutamine between neurons and astrocytes is known as the glutamate/GABA-glutamine cycle, which is crucial for maintaining excitatory and inhibitory neurotransmission (Andersen et al., 2022)

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Reviews of the rodent work note that the mechanism doesnt involve the hormonal suppression or receptor desensitization that would predict tolerance or rebound, and that adipose SAM levels tend to normalize rather than crash under inhibition