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53,54 However, it has also been suggested that the enhanced release of proinflammatory cytokines (TNF-, IL-1, IL-6, and IL-10) and chemokines (monocyte chemoattractant protein-1, macrophage inflammatory protein-2, and IL-8) further promotes hepatocyte damage, thereby aggravating necrosis

Progeny hermaphrodite animals were maintained at 20 C until the late L4 larval stage, and lifespan assays were counted as days after L4 stage

Thus, it is postulated that it is important to monitor CNI levels during the initial days of azole therapy and post-azole therapy (361)