liposomal glutathione: Zeylamum 2400 MG Glutathione Softgels, Max Absorption, Active Form L-Glutathione Reduced (GSH), with Hyaluronic Acid, Resveratrol, Master Antioxidants for Brain, Immune System, 120 Softgels : Health & Household Liposomal Glutathione - 60 capsules

FIGURE 4 This is complicated because as a polar, charged tripeptide, transport of GSH is significantly inhibited by the blood-brain barrier (BBB), thus limiting effective delivery to brain-resident immune cells such as microglia which are central drivers of neuroinflammatory pathology (Valdovinos-Flores and Gonsebatt, 2012

Acknowledgements The research was supported in part by the National Institutes of Health (R01-GM115622 and R01-CA207701 to J.W., R01-AG045183, R01-AT009050, R21-EB022302 and DP1-DK113644 to M.C.W., R01-GM120033 to M.M.-S., R01-NS100893 to M.X.), the Welch Foundation (Q-1912 to M.C.W.), Cancer Prevention and Research Institute of Texas (CPRIT R1104 to J.W., RP130573 to M.M.-S.), Whitehall Foundation Research Grant (2015-05-54 to M.X.), the Curtis Hankamer Basic Research Fund at Baylor College of Medicine (to M.X.), Caroline DeLuca Scholarship (to M.X.), the United States Department of Agriculture, Agricultural Research Service through Cooperative Agreement Number 58-6250-0-008 (to N.C.), the IDDRC Microscopy Core (P30HD024064 and 1U54 HD083092 Intellectual and Developmental Disabilities Research Grant from the Eunice Kennedy Shriver National Institute of Child Health and Human Development), the Optical Imaging and Vital Microscopy core, and the Cytometry and Cell Sorting Core at Baylor College of Medicine with funding from the NIH (AI036211, CA125123, and RR024574) and the expert assistance of Joel M

The remaining authors declare no competing financial interests

Therefore, these materials should be avoided during the sample preparation