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We synthesized a 40-base RNA oligonucleotide encompassing the cleavage site and found that it can be cleaved into the predicted fragments, which was completely inhibited by 48c (Fig

In this study, we found GPX3 knocked-down shortened the G0/G1 phase, up-regulated the expression of Cyclin D1, CDK4 and CDK6, and arrested G2 phase, which seemed to contradict the accelerated cell proliferation and decreased apoptosis led by GPX3 silenced