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Also, of importance are the interactions of these receptors with cancer directly or through the TME, which may also be impacted by oncogene expression

Lupeol reduced the growth of the chemosensitive HCC cell lines Huh-7 and PLC-8024 in nude mice, suppressed the growth of MHCC-LM3 cells, a chemoresistant HCC cell line, in a xenograft model and decreased CD133 expression levels in tumors

You can still do that, but you still get beautiful gelatinous broth with or without it, Ive tested both out, and it worked beautifully without it

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