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The overall total cellular amino acid concentrations were altered in the ATP6AP1 KO , with serine, a key amino acid induced by the mitochondrial stress response, remaining unchanged upon ACT treatment, and cysteine, important for glutathione synthesis, depleted from the media when compared to WT cells treated with ACT (Fig

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Overall, we found that methylphenidate, amphetamines, and atomoxetine were significantly more efficacious than placebo in improving QoL in people with ADHD

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