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1) Decipher cell type-specific ferroptosis regulatory networks: Use integrated single-cell multi-omics (scRNA-seq, Single-cell Assay for Transposase-Accessible Chromatin with High-throughput Sequencing (scATAC-seq), and single-cell metabolomics) to map ferroptosis-related gene expression, chromatin accessibility, and metabolite profiles across renal cell types in health and disease

10.1016/j.redox.2015.03.003 Redox Biol

The response of translational biomarkers can be compared the current gold standard translational biomarker ALT for better understanding the limitations and potential application in clinical setting