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However, overexpression of Pfkfb3 activates glycolysis in neurons through the APC/C-Cdh1 pathway, which inhibits the pentose phosphate pathway (PPP), reduces the oxidation of glucose-6-phosphate (G6P), decreases the production of reduced glutathione, and finally leads to oxidative stress and apoptosis (Herrero-Mendez et al., 2009)

NAC has shown neuroprotective effects in animal models and some clinical trials for ischemic stroke and neurodegenerative diseases, reducing oxidative stress and neuronal damage

These findings provide valuable evidence to counsel patients with hepatic adenoma undergoing IVF that monitoring the adenomas without intervention is likely safe and appropriate

5.5.3 Mesoporous Silica Nanoparticles (MSNPs) MSNPs possess a high surface area and well-ordered protective pore structure, exhibiting excellent chemical stability, biocompatibility, and biodegradability