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doi: 10.1186/1744-9081-10-14

Methylation is considered a key process in the synthesis of glutathione because part of the methylation cycle directly contributes to the production of cysteine, an essential amino acid needed to build glutathione molecules

Glucocorticoids bind to cytosolic glucocorticoid receptors and regulate gene expression by interacting with glucocorticoid response elements (GREs) in gene promoters