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Gut Microbes 13 , (2021)

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Effect of UDCA on the New Onset Diabetes and Glucose Intolerance Induced by Statin-A Multicenter, Prospective, Random Controlled Trial (2022)

N-methylthiourea is proposed to be the main methimazole reactive metabolite responsible for the hepatotoxicity induced by this drug.36 But, we recently showed that glyoxal also might has an important role in cellular injury induced by methimazole in an in vitro model of isolated rat hepatocytes.41 PTU is metabolized by glucuronidation in liver and prepared to exert from body (Fig