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The proposed mechanism involves PCs activating peroxisome proliferator-activated receptor (PPAR) in macrophages, upregulating PPAR target genes (CD36 and ABCG1) and driving the transition from M1 to M2 phenotypes

2017) vectors using a one-step cloning kit (Vazyme, Nanjing, China), and subsequently transformed into E

Several nutrients directly participate in ROS signaling and antioxidant defense

Oxidative stress in liver injury ROS include the free radicals superoxide (O 2 - ) and hydroxyl radical (HO - ) and non-radicals such as hydrogen peroxide (H 2 O 2 )