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Pickarts initial observation was that human albumin fractions containing GHK could regenerate aged liver tissue in culture a finding that launched the broader investigation into GHK Cus biological activity

When selecting therapies the nature and risk of these side effects must be taken into account

for developing a novel murine closed-skull traumatic brain injury (TBI) model and using it to demonstrate that the mouse skull, whether thinned or intact, is permeable to drugs, allowing "transcranial" drug delivery into the underlying cerebral cortex with consequent reduction in injury-related cell death when glutathione is delivered

IGF-1 is the readout