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Journal of Radioanalytical and Nuclear Chemistry 280 , 275279 (2009)

these bioactive molecules act on multiple targetsincluding EMT-related transcription factors and key signaling cascadesto effectively block epithelial-mesenchymal conversion, suppress myofibroblast activation and regulate aberrant extracellular-matrix (ECM) remodeling, thereby markedly curbing EMT progression and fibrotic disease ( Triptolide (TP), an active diterpenoid extracted from Tripterygium wilfordii Hook F, possesses anti-inflammatory, antiproliferative and immunomodulatory properties, and has been widely investigated in experimental idiopathic pulmonary fibrosis (IPF) models in recent years (102)

For conjugation methods that are not compatible with the stabilizing components present in this formulation, a carrier-free antibody format is required

Finally, linking data between public and private systems could enable continuous surveillance and equitable policy design