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Additionally, ethanol binge drinking induces neuroinflammation, such as indicated by the activation of innate immune receptors TLRs and by an increase in the expression of the inflammatory cytokines TNF and IL-1, and demyelination suggested by significantly reducing the levels of the myelin proteins myelin basic protein (MBP) and myelin oligodendrocyte glycoprotein (MOG) in the prefrontal cortex [123]

Can these injuries heal on their own

This work was partially supported by the University Grants Committee, Research Grants Council of Hong Kong (14113723, 14119124, 14121721), the Hong Kong Innovation Technology Commission Fund (GHP/186/22GD), and the Hong Kong Health and Medical Research Fund (09203436, 08190416)