glutathione reduces toxicity of epoxides

glutathione reduces toxicity of epoxides The Key Role GSH in Keeping the Redox Balance in Mammalian Cells: Mechanisms and Significance of GSH in Detoxification via Formation of Conjugates Epoxide Hydrolase - an overview

Name: glutathione reduces toxicity of epoxides The Key Role GSH in Keeping the Redox Balance in Mammalian Cells: Mechanisms and Significance of GSH in Detoxification via Formation of Conjugates Epoxide Hydrolase - an overview
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Epoxide Hydrolase an overview ScienceDirect Topics Glutathione Mediated Conjugation of Anticancer Drugs: An Overview of Reaction Mechanisms and Biological Significance for Drug Detoxification and Bioactivation Glutathione transferases: substrates, inihibitors and pro drugs in cancer and neurodegenerative diseases Oncogenesis Glutathione maintenance mitigates age related susceptibility to redox cycling agents ScienceDirect

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doi: 10.1016/j.jncc.2025.01.007 Summary Keywords colorectal cancer, microsatellite stable, antibody-drug conjugate, immunoconjugate, immuno-oncology Citation Wang Y, Lu K, Xu Y, Xu S, Chu H and Fang X (2025) Antibody-drug conjugates as immuno-oncology agents in colorectal cancer: targets, payloads, and therapeutic synergies