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The pro-inflammatory cytokines also play a crucial role in the neurodegenerative method, contributing to neuronal injury and cell death (35, 36)

In a mouse PD model induced by -synuclein preformed fibrils (PFFs), EGCG treatment decreased TNF- and IL-6 expression, reduced pathological aggregation, increased survival of dopaminergic neurons in the substantia nigra, and improved both motor and anxiety-like behaviors (53)

Autoantibodies against G-protein coupled receptors are found in ME/CFS patients and in patients with persistent long-COVID-19 symptoms (120, 121)

Here are some factors to consider: Health Conditions: NAC, known for its mucolytic properties, may be particularly beneficial for respiratory conditions such as COPD or asthma