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Participants received either a high-dose regimen (initial dose of 8,000 IU/day for two weeks, followed by 4,000 IU/day) or a standard-dose regimen (400 IU/day), in combination with mFOLFOX6 plus bevacizumab, continued until disease progression or unacceptable toxicity

PCOS is a risk factor for cardiometabolic diseases, gestational diabetes, and pregnancy complications

Human studies have shown that as the severity of liver fibrosis progresses, the number of hepatic progenitor cells increase, mimicking the pathological processes associated with the wound healing and carcinogenic response of the liver to injury which is observed in chronic viral hepatitis and alcohol-related liver disease [91, 92]

Mechanisms of reversible protein glutathionylation in redox signaling and oxidative stress