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In addition to clock transcripts, RLCs contained transcripts derived from 105 genes that were previously identified as clock-controlled in heads of young flies [ 17 ], supporting the notion that the circadian clock remains functional with age

However, a study investigating the effects of dietary supplements on weight management found that long-term use of B12 supplements was linked to less weight gain among middle-aged people over ten years 8

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J Biol Rhythms (2005) 20(5):391403