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PRP has been in the market for about five decades ago, and its first high profile use was in an open-heart surgery that was done in Italy in 1987

Incidentally these astrocytes did not possess ACE-2, known as a canonical SARS-CoV-2 gate into cells

To further inspect the biological and metabolic pathways in the DEGs of these cells after ZFPG + US treatment, the Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway and Gene Ontology (GO) analyses were employed