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(2016), Lin et al

Mechanistic support primarily comes from cellular and animal studies, which demonstrate that EGT protects endothelial cells from oxidative stress and may limit ischemiareperfusion damage and vascular dysfunction, rather than from large-scale human intervention trials

Thyroid hormones also reportedly alleviate NAFLD by enhancing FA oxidation, mitosis, and mitochondrial biogenesis [89, 90], as these hormones can increase mRNA expression of NIX, BNIP3, p62, ULK1, and LC3 under certain conditions to mediate mitophagy [91]