1d, benzophenone (C 6 H 5 COC 6 H 5 , t R 1.67, m/z 205.06 [M + Na] + ) (PubChem CID:3102), peak (c) (2S,3S)-4-benzyloxy-1-(tert-butyldimethylsi1yloxy)-3-methylbutan-2-ol (C 18 H 32 O 3 Si, t R 25.34, m/z 325.22 [M + H] + ), peak (d) denatonium (C 21 H 29 N 2 O + , t R 25.38, m/z 325.23 [M + H] + ) (PubChem CID:15488), peak (e) D-(+)-Cellobiose octaacetate (C 28 H 38 O 19 , t R 30.68, m/z 701.18 [M + Na] + ) (PubChem CID:107429), peak (f) 1-hydroxy Vitamin D 3 (C 27 H 44 O 2 , t R 46.07, m/z 383.33 [M + H-H 2 O] + ) (PubChem CID:5283731), peak (g) deoxykhivorin (C 32 H 42 O 9 , t R 46.10, m/z 593.27 [M + Na] + ) (PubChem CID:6708722), and peak (h) pheophytin A (C 55 H 74 N 4 O 5 , t R 51.92, m/z 871.57 [M + H] + ) (PubChem CID:135398712)
The Tank1 binding kinase (TBK1) is a critical regulator of various forms of autophagy via the phosphorylation of autophagy receptors, promoting autophagic flux 17
Oxidative stress is a key contributor to liver damage in NAFLD and is driven by an imbalance between reactive oxygen species (ROS) production and antioxidant defences in the liver
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