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In addition to this, pertussis toxin administration in the absence of ghrelin does not affect dopamine-associated cAMP accumulation, which typically signals through G s and G olf (Missale et al., 1998

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Because cortisol is an important regulator of redox homeostasis, reduced cortisol availability or altered glucocorticoid signaling may weaken anti-inflammatory and antioxidant defenses, thereby contributing to persistent oxidative stress

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