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The following sections detail how compromised AT propagates dysfunction through altered adipokine secretion, excessive free fatty acid release, inflammatory mediator production, and EV signaling, establishing self-perpetuating cycles that progressively worsen whole-body metabolic homeostasis

Eur J Hum Genet

Especially after the occurrence of COVID-19, a number of studies related to oxidative stress have been conducted, but they tend to be limited to inflammation and immunity only, ignoring the possible additional links with the older population, who are the most infected with CAP

Moreover, direct administration of cysteine to increase GSH is not a viable option, because of its poor absorption and toxicity at high doses (Johnson et al., 2012)