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For example, cimetidine acts as an OCT2 inhibitor that inhibits the transportation of cisplatin in the kidney to protect against AKI [64], carvedilol works as an antioxidant against the oxidative stress process [65], cilastatin inhibits the apoptotic pathway [66], and rosiglitazone reduces inflammation [67]

elegans mutants, which lack the redox-silent ferritin Fe 3+ storage pool, are short-lived and contain higher levels of pro-ferroptotic Fe 2+ (James et al., 2016)

Correlation of binding efficacies of DNA to flavonoids and their induced cellular damage

The birth cohorts were defined as 1)1895-1944 (pre-baby boomer)