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Tumor dimensions (length and width) and body weight were measured using a caliper every two days, and tumor volumes were calculated using the following formula: At the end of the experiment, the mice were euthanized, and whole blood, heart, liver, spleen, lungs, kidneys, tumor-draining lymph nodes (TDLNs), and tumors were harvested for imaging and weighing

Metabolic activity, namely glycolysis and oxidative phosphorylation, are drivers of immune cell function

Poor nutritional status is often associated with chronic alcoholism, and thus alcoholic patients with APAP-induced hepatotoxicity may fall victim to both decreased body GSH stores as well as enhancement of the CYP enzymatic activity