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Meyer DJ, Coles B, Pemble SE, Gilmore KS, Fraser GM, Ketterer B

Dihexa is not a conventional peptide but a peptidomimetic a small molecule (~504 Da) designed to mimic peptide binding activity while resisting enzymatic degradation

Nevertheless, several of these aspects have been successfully sorted out over recent years through the new technologies available in peptides design field: new bioinformatics tools in combination with other approaches such as virtual screening, structure-based drug design, high throughput screening (HTS) and chemical strategies, provide a comprehensive pharmacological description of putative peptides, improving their chemical and physical features (119, 121, 148)