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parkeri undergoes two temporally distinct phases of actin-based motility: an early phase mediated by RickA that results in short, curly actin tails, and a later phase mediated by Sca2 that results in long tails and is the major mediator of cell-to-cell spread 34,35,36,37

In addition, 817 drug-associated metabolites, 2,773 food-associated metabolites, 126 environment-associated metabolites, and 2,962 metabolites of unknown origin were identified (Figure 7B)