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Whats more, it can have adverse effects on quality of life

Immunoassay of insulin-like growth factor-binding protein-3 (IGFBP-3): new means to quantifying IGFBP-3 proteolysis

However, it remains unclear whether hepatic steatosis per se in MAFLD contributes to an elevated risk of mortality in individuals with overweight/obesity, metabolic dysregulation, or type 2 diabetes mellitus (DM) (referred to as the metabolic dysfunction-association (MA) group), which are known significant risk factors for increased mortality

Hyperglycaemia progressively impairs these transporters, accelerating beta-cell apoptosis and microvascular complications