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Neuroreport 5 , 25292533 (1994)

Long-term clinical effects of epalrestat, an aldose reductase inhibitor, on diabetic peripheral neuropathy: the 3-year, multicenter, comparative Aldose Reductase Inhibitor-Diabetes Complications Trial

Further, IGF-I appears to skew the accumulating HA molecules toward higher molecular weight species and to promote the proliferation of perimysial GD-OF (120)