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B Vitamins and Prevention of Cognitive Decline and Incident Dementia: A Systematic Review and Meta-Analysis

During oxidative stress, the oxidized DJ-1 may translocate to the outer membrane of mitochondria and it has been shown to prevent MPP + induced cell death, the mechanism of which remains unclear [12]

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Many metabolic pathways associated with mitochondria, such as the mitochondrial tricarboxylic acid cycle and electron transport chain, have the capability to generate ROS