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10.1080/19490976.2017.1353843 87 ConesaM

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For source design and surface treatment, MOFs could be constructed using low-toxicity metals such as iron and gallium, and COFs could be composed entirely of light elements to prevent the release of toxic metal ions at the source, thereby avoiding the immunological risks associated with such releases

The problem is, the first phase generates a burst of free radicals that can damage liver tissue if not quickly balanced by antioxidants