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T-cells are altered in ASD patients and the equilibrium between the different phenotypes is important in the progression of the disorder (Moaaz et al., 2019)

(3) It minimizes sustained membrane depolarization, raises the threshold for migraines, inhibits the release of CGRP and glutamate from the trigeminal vascular nerve endings, blocks high-voltage activated Ca 2+ channels, and reduces or prevents the release of neurotransmitters and vasoactive peptides (Dodick, 2018)