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Herein, we systematically summarize the currently reported representative drugs targeting mitochondria in cancer therapy and their underlying mechanisms of action ( Table 2 )

The GHSRGiscFV16 complex was purified and buffer-exchanged by size exclusion chromatography with buffer containing 20 mM HEPES pH 7.5, 100 mM NaCl, 0.002% MNG, 0.001% CHS, and 1 M ghrelin or ibutamoren

smegmatis strains expressing the Mtb TrxB2_TrxC operon The Mtb operon containing Rv3913 (trxB2) and Rv3914 (trxC) was expressed in M.smegmatis mc2155 using the integrating plasmid pCT94 under control of the constitutive promoter pUV15