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Your body converts cyanocobalamin into the two active forms of B12: methylcobalamin and adenosylcobalamin

Samir Sinha, who was not involved in the research, said B12 shots can't provide "a big boost." "Getting B12 shouldn't instantly make you feel great or more powerful," he said

The B12 injection itself is quick and virtually painless, typically administered in the upper arm or hip area

If folate deficiency is suspected, it is reasonable to give oral folic acid (0.4 1 mg/day) without doing laboratory investigation for deficiency at least until the hemoglobin and mean corpuscular volume normalizes (or longer if the underlying cause cannot be eliminated)