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As described above, estradiol positively regulates paraoxonase-2

Importantly, although several chemically-distinct agents, including glutamate, erastin, sulfasalazine and BSO, can all induce ferroptosis through GSH depletion, the present study extends our previous work by demonstrating that these diverse upstream perturbations converge on a shared downstream signaling axis centered on PDI

Another investigation demonstrated the anticolitic effect of carvacol is associated with the protection of mucosal barrier through reducing translocation of NF-B pathway and inhibiting TLR4 receptor activation pathway in DSS induced colitis model

Plant sterols: factors affecting their efficacy and safety as functional food ingredients