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Journal of Pharmaceutical and Biomedical Analysis, 252 , 116474

Chang et al., 2014), BPC 157induced promotion of the ex vivo outgrowth of tendon fibroblasts from tendon explants, cell survival under stress, and the in vitro migration of tendon fibroblasts are the effects mediated by the activation of the focal adhesion kinase (FAK)paxillin pathway (Chang et al., 2011

For a comprehensive review of these mechanisms, a peer-reviewed study in Cell and Tissue Research documenting the role of gastric pentadecapeptide BPC-157 in accelerating musculoskeletal soft tissue healing lays out the signaling cascade in detail