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AZT and d4T induce a rapid increase in mitochondrial proliferation in human fibroblasts (Caron et al., 2008), and their combination with or without IDV increase mitochondrial mass in both white and brown murine adipocytes (Viengchareun et al., 2007)

Briefly, the slides are transferred to a solution of 0.06% potassium permanganate for 10 min, preferably on a shaker table to insure consistent background suppression between sections

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The extract demonstrated a favorable safety profile, characterized by the absence of significant adverse events or laboratory abnormalities