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Combination therapy using PARP and ATR inhibitors has shown promising results in clinical trials, particularly in platinum-resistant HGSOC patients (127)

Saad K, Zahran AM, Elsayh KI, Abdel-Rahman AA, Al-Atram AA, Hussein A, El-Gendy YG (2017) Frequency of dendritic cells and their expression of costimulatory molecules in children with autism spectrum disorders

1 Introduction Acute respiratory distress syndrome (ARDS) is a severe, life-threatening inflammatory condition of the lungs commonly triggered by infections such as bacterial pneumonia, viral pathogens (e.g., influenza and SARS-CoV-2), and systemic sepsis ( The pathogenesis of ARDS involves an exaggerated immune response that damages alveolar structures, disrupts the alveolar-capillary barrier, and promotes excessive inflammation, vascular leakage, and oxygenation failure ( Regulated cell death pathways, such as apoptosis, pyroptosis, necroptosis, and ferroptosis, play pivotal roles in controlling inflammation and maintaining tissue integrity

Mukherjee C, Kling T, Russo B, Miebach K, Kess E, Schifferer M, et al