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The usual clinical course for people so treated is to have initially improved glycemic control but over time a need for intensification of drug-based treatment of hyperglycemia

The roles of cytochromeb5 in cytochrome P450 reactions

BNIP3, a member of the pro-apoptotic protein family, is upregulated in response to hypoxic conditions and has been implicated in the induction of autophagic cell death (93)