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The subsequent triumphs in clinical trials paved the way for the approval of other anti-PD-1 mAbs, such as pembrolizumab, camrelizumab, sintilimab, toripalimab, and nivolumab, for treating a diverse range of malignancies [99]

In addition, we performed a thorough phylogenetic analysis of all the consensus sequences found in all the studied GTs to rule out the possibility of cross-contamination between samples in our Roche-NGS experiments