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ROS can damage essential components of the muscle cell, such as cellular lipids, DNA, and mitochondria, which in turn promotes the apoptosis of muscle cells (38, 55)

In patients with G6PD deficiency, there is a decrease in the formation of NADPH according to the degree of deficiency and the degree of the activity of the enzyme, by which the World Health Organization classify the disease

Contraindications/Precautions Cyanocobalamin is contraindicated in those with hypersensitivity to cobalt moiety or cobalamin molecule due to the risk of anaphylaxis (9)

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